Research Article
Triptolide Inhibits Th17 Response by Upregulating microRNA-204-5p and Suppressing STAT3 Phosphorylation in Psoriasis
Figure 7
Effects of triptolide on miR-204-5p and STAT3 expression in psoriasis-like lesions. (a and b) After collecting the dorsal skin of mouse models in the indicated groups on the 8th day, RT-qPCR was performed for examining miR-204-5p and STAT3 expression. (c) The expression correlation between miR-204-5p and STAT3 by Spearman’s correlation analysis. (d–f) The protein levels of STAT3 and p-STAT3 in the dorsal skin of mouse models tested via Western blot analysis. Each column is representative of data obtained from a minimum of 8 animals. ## compared to the sham group; , compared to the model group.
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