Association of Endothelin-Converting Enzyme and Endothelin-1 Gene Polymorphisms with Essential Hypertension in Malay Ethnics

Table 1

Clinical and biochemical parameter of EH patients and control subjects.

Parameter	Control (%)	Case (%)
No. of samples	196	177
Age	37.17 ± 9.408	57.02 ± 9.516	<0.001
Gender
Male	98 (50.0%)	106 (59.9%)	0.056
Female	98 (50.6%)	71 (40.0%)
BMI	23.58 ± 3.82	28.77 ± 4.64	<0.001
WHR	0.91 ± 0.14	0.899 ± 0.098	<0.001
FPG	5.50 ± 1.38	6.55 ± 2.42	<0.001
HbA1c	2.73 ± 2.93	6.47 ± 1.87	<0.001
SBP	121.52 ± 10.24	156.80 ± 12.13	<0.001
DBP	78.21 ± 7.43	94.49 ± 5.8	<0.001
Cholesterol	4.83 ± 0.93	5.04 ± 1.10	0.049
LDL	2.63 ± 0.94	2.86 ± 0.88	0.20
HDL	1.10 ± 0.35	1.25 ± 0.74	0.015
TG	1.46 ± 0.65	1.85 ± 0.99	<0.001

Note: BMI = body mass index; WHR = waist-to-hip ratio; FPG = fasting plasma glucose; HbA1c = hemoglobin A1c; SBP = systolic blood pressure; DBP = diastolic blood pressure; Chol = cholesterol; LDL = low-density lipid; HDL = high-density lipid; TG = triglyceride.