Association of Endothelin-Converting Enzyme and Endothelin-1 Gene Polymorphisms with Essential Hypertension in Malay Ethnics

Table 3

Genotype and allele frequencies of ECE rs212526 polymorphism.

Group		Control (%)	Case (%)	^a	OR	95% CI LL	95% CI UL
Genotype	CC	12 (6.1)	19 (10.7)	<0.001	2.274	1.063	4.863
	CT	16 (8.2)	41 (23.2)		3.679	1.971	6.868
	TT	168 (85.7)	117 (66.1)		Ref
Allele
	C	40 (10.2)	79 (23.3)	<0.001	2.528	1.675	3.816
	T	352 (89.8)	275 (77.7)		Ref
DOM	CC + CT	28 (14.3)	60 (33.9)	<0.001
RES	TT + CT	184 (93.9)	158 (89.3)	<0.001
	Post hoc test	Χ^2	value^a
	CC vs. CT	0.811	0.36
	CC vs. TT	8.6	0.0033
	CT vs. TT	10.156	0.0014

Note: HOM MT = Homozygous mutant; HET = heterozygous; WT = wild type; DOM = dominant; RES = recessive. ^aChi-square test.