Association of Endothelin-Converting Enzyme and Endothelin-1 Gene Polymorphisms with Essential Hypertension in Malay Ethnics

Table 5

Clinical and biochemical characteristics according to genotypes of ECE rs212526 gene polymorphism.

Parameter	Control (mean ± SD)				Case (mean ± SD)
	CC	CT	TT	^a	CC	CT	TT	^a
Age	33.58 ± 4.76	42.56 ± 11.4	36.92 ± 9.3	0.028	58 ± 4.68	57.32 ± 9.39	56.76 ± 10.16	0.85
BMI	22 ± 1.36	24.74 ± 4.64	23.59 ± 3.84	0.174	31.66 ± 4.41	28.75 ± 4.88	28.31 ± 4.47	0.014
WHR	0.86 ± 0.08	1.03 ± 0.27	0.9 ± 0.13	0.002	0.86 ± 0.23	0.91 ± 0.06	0.9 ± 0.06	0.24
FPG	5.19 ± 0.91	5.75 ± 1.16	5.51 ± 1.44	0.59	7.71 ± 3.4	6.65 ± 2.49	6.34 ± 2.19	0.104
HbA1c	1.04 ± 2.33	3.37 ± 3.11	2.79 ± 2.93	0.091	6.26 ± 3.2	6.92 ± 1.94	6.37 ± 1.53	0.248
SBP	114.67 ± 10.75	121.44 ± 10.6	122.02 ± 10.06	0.055	156.53 ± 9.77	157.88 ± 12.09	156.48 ± 12.56	0.814
DBP	72.58 ± 5.81	77.13 ± 7.24	78.73 ± 7.41	0.017	92.42 ± 5.95	95.95 ± 5.7	94.33 ± 5.78	0.082
Chol	5.14 ± 1.04	4.73 ± 1.32	4.82 ± 0.89	0.468	4.95 ± 1.02	5.11 ± 1.25	5.04 ± 1.07	0.871
LDL	3.15 ± 0.88	2.34 ± 0.91	2.63 ± 0.95	0.074	2.76 ± 0.83	2.75 ± 0.98	2.92 ± 0.86	0.492
HDL	1.16 ± 0.29	1.04 ± 0.41	1.1 ± 0.35	0.664	1.28 ± 0.4	1.19 ± 0.35	1.27 ± 0.88	0.854
TG	1.64 ± 0.53	1.4 ± 0.44	1.46 ± 0.68	0.621	1.68 ± 0.88	1.92 ± 1.22	1.86 ± 0.93	0.679

Note: SD = standard deviation; BMI = body mass index; WHR = waist-to-hip ratio; FPG = fasting plasma glucose; HbA1c = hemoglobin A1c; SBP = systolic blood pressure; DBP = Diastolic blood pressure; Chol = cholesterol; LDL = low-density lipid; HDL = high-density lipid; TG = triglyceride. ^aOne-way ANOVA.