Association of Endothelin-Converting Enzyme and Endothelin-1 Gene Polymorphisms with Essential Hypertension in Malay Ethnics

Table 6

Genotypic distribution in female and male.

Gene	Gender	Genotype	Control n (%)	Case n (%)	value	OR	95% CI LL	95% CI UL
ET-1	Male	GG	77 (78.6)	9 (8.5)	<0.001	Ref
		GT	14 (14.3)	31 (29.2)	<0.001	23.178	5.618	95.629
		TT	7 (7.1)	66 (62.3)	<0.001	71.696	14.69	349.912
	Female	GG	71 (72.4)	7 (9.9)	<0.001	Ref
		GT	17 (17.3)	15 (21.1)	0.185	2.764	0.614	12.433
		TT	10 (10.2)	49 (69)	<0.001	13.683	3.339	56.061
ECE	Male	CC	5 (5.1)	8 (7.5)	0.736	0.83	0.078	8.847
		CT	9 (9.2)	24 (22.6)	0.837	1.306	0.103	16.574
		TT	84 (85.7)	74 (69.8)	0.877	Ref
	Female	CC	7 (7.1)	11 (15.5)	0.34	0.348	0.05	2.404
		CT	7 (7.1)	17 (23.9)	0.799	0.751	0.083	6.809
		TT	84 (85.7)	43 (60.6)	0.284	Ref

Notes: CI = confidence interval; the analysis was adjusted based on age and BMI as covariates.