Research Article

Regulation of Hepatocytes in G0 and G1 Phases by NOTCH3 mRNA, miR-369-3p, and rno-Rmdn2_0006 during the Initial Stage of Rat Liver Regeneration

Table 2

Expression correlation of NOTCH3 and the NOTCH3-regulated G0 phase- and G1 phase-related genes of hepatocytes.

mRNAExpression of NOTCH3 and the NOTCH3-regulated genes
Control0 h6 hSignificance

NOTCH3 mRNA1 ± 01.53 ± 1.142.53 ± 2.600.00
G0 phase-related genes
 NOTCH3-promoted
  CDKN1c1.003.05 ± 1.271.08 ± 0.470.00
 NOTCH3-inhibited
  CDKN1a1.000.39 ± 0.070.93 ± 0.150.00
G1 phase-related genes
 NOTCH3-promoted
  CHUK1.001.00 ± 0.171.52 ± 0.140.00
  DDX241.000.78 ± 0.111.63 ± 0.110.00
  HES11.001.07 ± 0.111.80 ± 0.160.00
  NET11.000.87 ± 0.142.03 ± 0.060.00
  STAT31.000.74 ± 0.152.88 ± 0.240.00
 NOTCH3-inhibited
  PSEN21.001.07 ± 0.210.45 ± 0.060.00

Extremely significant.