Genetics Research International

Genetics of Deafness


Publishing date
01 Nov 2011
Status
Published
Submission deadline
01 May 2011

Lead Editor

1Center for Molecular Biology and Genetic Engineering, State University of Campinas, Campinas, SP, Brazil

2Department of Microbiology and Molecular Genetics and Pediatrics/Human Development, College of Natural Science, Michigan State University, East Lansing, MI 48824, USA

3Hospital Ramon y Cajal, Unidad de Genética Molecular, Madrid, Spain


Genetics of Deafness

Description

In front of great advances in physiological and molecular aspects in hearing area, every day it becomes more evident that the continuing molecular and physiological advances in hearing research require the exchange of knowledge between otolaryngologists, speech-language pathologists, and basic scientists, particularly geneticists.

Deafness is an etiologically heterogeneous trait, with many known genetic and environmental causes. It is estimated that 10% of the world population has hearing loss, requiring some form of aid for communication. Deafness represents a challenge that has a severe effect on the individual and those ones who live with him, becoming a major obstacle for daily communication.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing effort to determine the molecular genetic basis of deafness. Understanding molecular mechanisms associated with development and function of the hearing organ aim to pave the way for research into therapeutic tools and to inform public policies for planning of programs and investments. Potential topics include, but are not limited to:

  • Mapping genes of deafness
  • Genes expressed in the inner ear
  • Using mouse mutants to study deafness
  • Micro-RNA and hearing impairment
  • Mitochondrial mutations and hearing loss
  • Age-related and noise-induced hearing impairment
  • Syndromic and nonsyndromic hearing loss
  • Molecular diagnosis of inherited hearing impairment
  • The epidemiology of hereditary deafness
  • Genetic testing for deafness and newborn hearing screening
  • Inner ear gene therapy
  • Social aspects of genetic counseling for deafness patients

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/gri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 562848
  • - Editorial

Genetics of Deafness

Edi Lúcia Sartorato | Karen Friderici | Ignacio Del Castillo
  • Special Issue
  • - Volume 2012
  • - Article ID 856157
  • - Review Article

The Molecular Biology of Vestibular Schwannomas and Its Association with Hearing Loss: A Review

Erika Celis-Aguilar | Luis Lassaletta | ... | Juan A. Rey
  • Special Issue
  • - Volume 2012
  • - Article ID 287432
  • - Clinical Study

Mitochondrial Sensorineural Hearing Loss: A Retrospective Study and a Description of Cochlear Implantation in a MELAS Patient

Mauro Scarpelli | Francesca Zappini | ... | Giuliano Tomelleri
  • Special Issue
  • - Volume 2011
  • - Article ID 983942
  • - Review Article

Hearing Loss in Osteogenesis Imperfecta: Characteristics and Treatment Considerations

Joseph P. Pillion | David Vernick | Jay Shapiro
  • Special Issue
  • - Volume 2011
  • - Article ID 787026
  • - Research Article

Clinical Application of Screening for GJB2 Mutations before Cochlear Implantation in a Heterogeneous Population with High Rate of Autosomal Recessive Nonsyndromic Hearing Loss

Masoud Motasaddi Zarandy | Mersedeh Rohanizadegan | ... | Mahdi Malekpour
  • Special Issue
  • - Volume 2011
  • - Article ID 294675
  • - Research Article

Autosomal Recessive Nonsyndromic Hearing Impairment due to a Novel Deletion in the RDX Gene

Kwanghyuk Lee | Mohammad Amin ud Din | ... | Suzanne M. Leal
  • Special Issue
  • - Volume 2011
  • - Article ID 416450
  • - Review Article

The Sound of Silence: Mouse Models for Hearing Loss

Sumantra Chatterjee | Thomas Lufkin
  • Special Issue
  • - Volume 2011
  • - Article ID 827469
  • - Research Article

Assessing Noncoding Sequence Variants of GJB2 for Hearing Loss Association

T. D. Matos | H. Simões-Teixeira | ... | G. Fialho
  • Special Issue
  • - Volume 2011
  • - Article ID 368915
  • - Research Article

A Novel ESRRB Deletion Is a Rare Cause of Autosomal Recessive Nonsyndromic Hearing Impairment among Pakistani Families

Kwanghyuk Lee | Saadullah Khan | ... | Suzanne M. Leal
  • Special Issue
  • - Volume 2011
  • - Article ID 587602
  • - Research Article

Molecular Investigation of Pediatric Portuguese Patients with Sensorineural Hearing Loss

Célia Nogueira | Miguel Coutinho | ... | Laura Vilarinho