Nicotine Enemas for Active Crohn's Colitis: An Open Pilot Study

Table 2

Baseline characteristics of 10 patients with Crohn’s colitis. Extent of disease: 1 = proctitis, 2 = sigmoid colon, 3 = descending colon, 4 = transverse colon, 5 = ascending colon, 6 = pancolitis, 7 = ileal, 8 = perianal. “Recent enemas” refers to any steroid or 5 aminosalicylate (5-ASA) enemas taken from 1 to 3 weeks before entry into the study. All concomitant medication doses given are the daily amounts, the only oral steroid taken was prednisolone, aza = azathioprine. CDAI = Crohn’s disease activity index.

No.	Age (years)	Sex	Exsmoker	Disease extent	Duration relapse (weeks)	Recent enemas	5-ASA (g)	Oral steroids (mg)	Aza (mg)	Baseline CDAI score
1	41	M	−	1,2,3,4	>99	−	−	−	−	73
2	27	M	+	1	1	−	−	−	−	156
3	52	F	+	6,7	>99	−	−	10	−	150
4	59	M	+	2,5	7	−	3.2	−	150	246
5	73	M	+	6	>99	−	2.4	10	−	200
6	38	M	−	6,8	9	−	−	−	−	167
7	59	F	+	2,3,4	>99	−	1.2	−	−	272
8	79	M	+	3,4	30	−	−	−	−	259
9	27	M	−	1	1	−	3.0	−	−	144
10	62	F	+	2,3	5	foam	2.4	−	50	348