Treatment of Chronic Hepatitis C in a Patient Affected by Systemic Sclerosis

Table 2

International scoring system for diagnosis of autoimmune hepatitis. This scoring system defines a “definitive autoimmune hepatitis” for values >+15 before treatment; “probable autoimmune hepatitis” is defined for values between 10, and 15 before treatment. Our patient presented total score +5 (very unlikely diagnosis of autoimmune hepatitis).

Parameter	Patient’s results	Score	Parameter	Patient’s results	Score
Gender	Female	+2	Hepatotoxic dugs exposure	No	+1
AP : AST ratio	<3.0	+2	Alcohol	<25 g/day	+2
𝛾-globulin level above-normal	1.0–1.5	+1	HLA DR3 o DR4	No	0
Autoantibodies	ANA > 1 : 80	+3	Other autoimmune disease	yes	+2
Antimitochondrial Antibodies	Negative	0	Other markers	Negative	0
Viral markers	HCV RNA positive	−3	Histological features	None	−5

AP : AST ratio: ratio of alkaline phosphatase level to aspartate aminotransferase level; ANA: antinuclear antibodies.