Gastroenterology Research and Practice / 2009 / Article / Tab 4 / Research Article
Tumor Necrosis Factor Receptor Superfamily, Member 1B Haplotypes Increase or Decrease the Risk of Inflammatory Bowel Diseases in a New Zealand Caucasian Population Table 4
Genotype and allele counts for TNFRSF1B
variants in New Zealand IBD patients and in New Zealand Caucasians.
SNP Controls CD UC CD + UC IC N(%) N(%) OR (95% CI) N(%) OR (95% CI) N(%) OR (95% CI) N(%) TNFRSF1B_1061622 GG 12
(4.1) 18
(4.7) 1.12
(
) 23
(5.8) 1.42
(
) 41
(5.2) 1.27
(
) 0 GT 102
(34.8) 144
(37.6) 1.17
(
) 154
(38.6) 1.22
(
) 298
(38.1) 1.19
(
) 8 (30.8) TT 179
(61.1) 221
(57.7) 1.00 222
(55.6) 1.00 443
(56.6) 1.00 18 (69.2) Genotype P -value 0.67 0.29 0.38 HWE P -value .73 .37 .58 .32 G 126
(21.5) 180
(23.5) 200
(25.1) 380
(24.3) 44 (84.6) T 460
(78.5) 586
(76.5) 598
(74.9) 1184
(75.7) 8 (15.4) OR (95% CI) 1.12
(
) 1.22
(
) 1.17
(
) Allelic P -value .38 .12 .17 TNFRSF1B_1061624 AA 65 (22.2) 94 (24.5) 1.00 96 (24.1) 1.00 190 (24.3) 1.00 4 (16.0) AG 158 (53.9) 185 (48.3) 0.85 (
) 185 (46.4) 0.84 (
) 370 (47.3) 0.85 (
) 20 (80.0) GG 70 (23.9) 104 (27.2) 1.05 (
) 118 (23.9) 1.21 (
) 222 (28.4) 1.13 (
) 1 (4.0) Genotype P -value 0.43 0.12 0.16 HWE P -value .20 .51 .16 .14 A 288 (49.1) 373 (48.7) 377 (47.2) 750 (48.0) 28 (56.0) G 298 (50.9) 393 (51.3) 421 (52.8) 814 (52.0) 22 (44.0) OR (95% CI) 0.98 (
) 0.93 (
) 0.95 (
) Allelic P -value .87 .48 .62 TNFRSF1B_3397 CC 112 (38.2) 135 (35.2) 1.00 165 (41.4) 1.00 300 (38.4) 1.00 11 942.3) CT 138 (47.1) 186 (48.6) 1.22 (
) 169 (42.4) 0.88 (
) 355 (45.4) 1.03 (
) 11 (42.3) TT 43 (14.7) 62 (16.2) 1.29 (
) 65 (16.3) 1.09 (
) 127 (16.2) 1.18 (
) 4 (15.4) Genotype P -value .70 .46 .79 HWE P -value 1.00 0.88 0.05 0.20 C 362 (61.8) 456 (59.5) 499 (62.5) 955 (61.1) 33 (63.5) T 224 (38.2) 310 (40.5) 299 (37.5) 609 (38.9) 19 (36.5) OR (95% CI) 0.91 (
) 1.03 (
) 0.97 (
) Allelic P -value .40 .77 .76
