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Gastroenterology Research and Practice
Volume 2009, Article ID 713937, 4 pages
Case Report

ABO Incompatible Liver Transplantation as a Bridge to Treat HELLP Syndrome

1Department of Liver Transplantation, Piedmont Hospital, Atlanta, GA 30309, USA
2Liver Center of Atlanta, Piedmont Hospital, Atlanta, GA 30309, USA
3Department of Pathology, Piedmont Hospital, Atlanta, GA 30309, USA

Received 21 December 2008; Revised 10 June 2009; Accepted 12 July 2009

Academic Editor: John Plevris

Copyright © 2009 Kathleen Connor et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The following is a case report of a primiparous woman who developed fulminant liver failure in the setting of HELLP syndrome complicated by hepatic rupture. It is unique in that a timely ABO compatible liver donor was unavailable, necessitating the transplantation of an ABO incompatible organ. Despite aggressive therapy, severe reperfusion injury and humoral rejection dictated retransplantation with an ABO compatible organ on postoperative day 15, resulting in rapid clinical recovery.