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Gastroenterology Research and Practice
Volume 2009, Article ID 835258, 5 pages
Case Report

Characterization of Follicular Lymphoma in the Small Intestine Using Double-Balloon Endoscopy

1Department of Gastroenterology and Hepatology, Iwate Medical University, Morioka, Iwate 020-8505, Japan
2Ministry of Health and Family Welfare, Government of Bangladesh, Polash, Narshingdi, Bangladesh
3Division of Molecular Diagnostic Pathology, Department of Pathology, Iwate Medical University, Morioka, Iwate 020-8505, Japan

Received 23 March 2009; Accepted 30 July 2009

Academic Editor: Matthew Shale

Copyright © 2009 Manzurul Chowdhury et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Follicular lymphomas occur rarely in the gastrointestinal tract, representing only 1–3% of all gastrointestinal tract B-cell non-Hodgkin lymphomas. We describe endoscopic analysis of 3 cases of follicular lymphoma in the small intestine using double-balloon endoscopy. Double-balloon endoscopy revealed multiple nodular lesions and elevated white patches, multiple polypoid lesions, and scattered white polypoid and nodular lesions in the duodenum and small intestine. Fuji Intelligent Chromo Endoscopy demonstrated small, whitish nodules, and narrow-band imaging showed a coiled, elongated vascular pattern within the elevated lesions. These cases are the first follicular lymphomas in the small intestine evaluated using narrow-band imaging or Fuji Intelligent Chromo Endoscopy to be reported.