Rat Strain Differences in Susceptibility to Alcohol-Induced Chronic Liver Injury and Hepatic Insulin Resistance

Figure 2

Rat strain differences in susceptibility to alcohol-induced steatohepatitis: histological sections of liver were stained with (a)–(l) H&E. Photomicrographs depict livers from (a, c, e, g, i, k) control or (b, d, f, h, j, l) ethanol-exposed (a)–(d) FS, (e)–(h) LE, or (i)–(l) SD rats. Note more prominent microsteatosis (vacuoles) and apoptosis (arrows) in ethanol-fed LE and SD compared with FS rats, and in ethanol-fed relative to control rats. Also, note microsteatosis in LE control livers (g). Original magnifications, Panels ((a), (b), (e), (f), (i), (j)): 80x, Panels ((c), (d), (g), (h), (k), (l)): 400x, Insets:650x.

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