Involvement of COX-2/PGE₂ Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer

Figure 2

Expression of COX-2 and MMP-9 in pancreatic cancer cell lines. (a) Expression of COX-2 and MMP-9 was detected in pancreatic cell lines BxPC-3, Capan-1, PANC-1, and AsPC-1 by Western blotting. (b) PGE₂ protein in the culture supernatant of BxPC-3 and Capan-1 cells was measured by Elisa. Data are expressed as mean ± SD, 𝑛=3.

(a)

(b)