Involvement of COX-2/PGE₂ Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer

Figure 6

Upregulation of MMP-9 by exogenous PGE₂ Western blotting (a) and real-time PCR (b) revealed MMP-9 was upregulated in BxPC-3 cells treated with 50 μmol/L (*𝑃<0.01, versus 0 μmol/L) or 100 μmol/L (*𝑃<0.01, versus 0 μmol/L). Data are expressed as mean ± SD, 𝑛=3.

(a)

(b)