Connexin43 Expression Increases in the Epithelium and Stroma along the Colonic Neoplastic Progression Pathway: Implications for Its Oncogenic Role
Figure 6
The relationship between Cx43 expression and nuclear beta-catenin expression in colonic adenocarcinoma (original magnification ×200). (a) Coexpression of Cx43 (brown cytoplasmic staining) and nuclear beta-catenin (red nuclear staining). Note. Peritumoral stromal cells exhibited only Cx43 but not beta-catenin reactivity. (b) Tumoral tissue exhibited heterogeneous expression of Cx43 and nuclear beta-catenin. (c) Tumoral tissue with expression of Cx43 only. (d) Tumoral tissue with expression of beta-catenin only. (e) Tumoral tissue with no expression of Cx43 or beta-catenin.
