Liver Regeneration after Partial Hepatectomy Is Not Impaired in Mice with Double Deficiency of Myd88 and IFNAR Genes
Figure 3
Liver regeneration after PH in C57Bl6 WT and Myd88-IFNAR double-KO mice without preexisting liver lesions. Shown are (a) the mean number of BrdU-labeled hepatocytes, (b) the total number of mitotic figures in hepatocytes, and (c) the mean number of BrdU-labeled nonparenchymal liver cells (NPCs), counted in eight 200x microscopic fields per mouse liver in C57Bl6 WT mice (white bars) and in Myd88-IFNAR double-KO mice (black bars) at the indicated times after PH or sham laparotomy. The number of mice in each group is indicated below the -axis. *. (d) Liver-to-body weight ratios in C57Bl6 WT (white circles) and Myd88-IFNAR double-KO mice (black circles), measured at the indicated time points after PH or sham laparotomy.
