Clinical Study
The Histological and Immunohistochemical Aspects of Bile
Reflux in Patients with Gastroesophageal Reflux
Disease
Table 4
Endoscopic and histologic data in BRI-positive and BRI-negative GERD patients.
| | BRI-positive
() | BRI-negative
() |
| | Esophagus | |
| | Endoscopy, n (%) | | | | Esophagitis Grade | | | | 0 | 7 (28) | 13 (46.4) | | A | 5 (20) | 10 (35.7) | | B | 8 (32) | 5 (17.8) | | C | 3 (12) | 0 | | D | 0 | 0 | | Barrett’s | 3 (12) | 0 | | Hernia | 10 (40) | 8 (28.5) | | Presence of bile | 2 (8) | 2 (7) | | Histology, n (%) | | | | Esophagitis | 22 (88) | 23 (82.1) | | Barrett’s | 3 (12) | 0 | | Dysplasia | 0 | 0 |
| | Stomach | |
| | Endoscopy, n (%) | | | | Gastritis | | | | No | 3 (12) | 8 (28.5) | | Mild | 15 (60) | 15 (53.5) | | Erosive | 7 (28) | 5 (17.8) | | Presence of bile | 13 (52) | 14 (0.5) | | Histology, n (%) | | | | Gastritis | 24 (96) | 26 (92.8) | | Atrophy | 11 (44) | 6 (21.4) | | H. pylori | 3* (12) | 13 (46.4) | | Cardiac metaplasia | 5 (20) | 1 (3.5) | | Antrum metaplasia | 9* (36) | 3 (10.7) | | Dysplasia | 0 | 0 |
|
|
Statistically significant differences are marked with asterisk (*).
|
