Reduced FAF1 Expression and Helicobacter Infection: Correlations with Clinicopathological Features in Gastric Cancer

Table 1

FAF1 mRNA expression and clinicopathological characteristics of gastric cancer.

Parameter	𝑛	FAF1 mRNA level**	𝑡(𝐹)	𝑃
Gender
Female	11	0.27 ± 0.12	0.192	0.849
Male	29	0.26 ± 0.11
Age (years)
≥60	17	0.27 ± 0.12	0.53	0.599
<60	23	0.25 ± 0.11
Tumor size (cm)*
≥5	18	0.26 ± 0.11	0.1	0.921
<5	22	0.26 ± 0.12
Histological grade
Well differentiated	14	0.39 ± 0.06	9.966	<0.001
Poorly differentiated	26	0.19 ± 0.06
Invasion depth
No serosa invasion	7	0.30 ± 0.12	1.09	0.283
Serosa invasion	33	0.25 ± 0.11
Lymph node metastasis
Present	3	0.34 ± 0.14	1.266	0.213
Absent	37	0.25 ± 0.11
Distant metastasis
Present	12	0.19 ± 0.07	−2.753	0.009^a
Absent	28	0.29 ± 0.12
Clinical stage
I + II	8	0.32 ± 0.12	6.276	0.004^a
IIIA + IIIB	17	0.30 ± 0.11
IV	15	0.18 ± 0.12

*Defined by the longest dimension in the gastric mucosa.
**Normalized to the level of 𝛽-actin.
^a𝑃<0.01, based on a comparison using a mean ± SD test.