Research Article

Systemic Chemotherapy prior to Cytoreductive Surgery and HIPEC for Carcinomatosis from Appendix Cancer: Impact on Perioperative Outcomes and Short-Term Survival

Table 2

Comparison of perioperative variables between 34 patients treated with neoadjuvant chemotherapy prior to cytoreductive surgery and HIPEC and 24 patients that did not receive preoperative chemotherapy before cytoreductive surgery and HIPEC.

Clinical characteristicPatients with PMCA from appendix cancer
Neoadjuvant chemotherapyNo neoadjuvant chemotherapyP value

Number of patients3424
Peritoneal cancer index (mean)19280.0003
Number of peritonectomies0.0032
 Mean2.33.7
 Range0–51–5
Number of visceral resections<0.001
 Mean2.74.4
 Range1–52–7
Completeness of cytoreduction0.78
 CCR 0/CCR 12212
 CCR 275
 CCR 355
Complications0.16
 None or grade1/2810
 Grade 3 or 42614