Probiotics, Symptoms, and Gut Microbiota: What Are the Relations? A Randomized Controlled Trial in Subjects with Irritable Bowel Syndrome

Table 3

Predictors for “treatment effect” (increase in symptoms during active treatment minus increase during placebo treatment).

Independent variables	Statistics
	𝛽	𝑃 values
Active treatment	3.03–3.20	𝑃=0.029–0.035
Bacteroides	1.59	ns (𝑃=0.74)
Faecalibacterium	−0.02	ns (𝑃=0.99)
Lachnospiraceae	−1.39	ns (𝑃=0.73)
“Common” Simpson’s D	−0.39	ns (𝑃=0.92)

The table gives the results of four linear regression analyses. “Treatment effect” is a dependent variable, and treatment is an independent variable in all analyses; changes in Simpson’s diversity score and the proportions of Bacteroides, Faecalibacterium, and Lachnospiraceae are independent variables in each of the four analyses.