Figure 1: Representative example of loss of heterozygosity (LOH) and microsatellite instability (MSI). Seven loci that linked to tumor suppressor genes were used to identify significant structural chromosomal aberrations (D5S505, D10S501, D10S602, TP53, D17S855, D18S58 and D18S61). Microsatellite status was investigated for two different microsatellite marker loci (BAT25 and BAT26). (NL: normal; T: tumor).