Research Article
Vitamin D Receptor Polymorphisms Predispose to Primary Biliary Cirrhosis and Severity of the Disease in Polish Population
Table 3
Allele association for VDR in patients with PBC and control subjects.
| | SNP | Allele | PBC (%) | Controls (%) | OR (95% CI) | |
| rs1544410
(BsmI) | G/A
(b/B) | 115 (40.2%)/171 (59.8%) | 320 (53.2%)/282 (46.8%) | 1.69 (1.27–2.24) | 0.0003 | rs7975232
(ApaI) | G/T
(a/A) | 160 (56%)/126 (44%) | 311 (51.7%)/291 (48.3%) | 0.84 (0.63–1.2) | 0.25 | rs731236
(TaqI) | T/C
(T/t) | 117 (41%)/169 (59%) | 364 (60.5%)/238 (39.5%) | 0.62 (0.47–0.82) | 0.0001 |
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PBC: primary biliary cirrhosis; OR: odds ratio; CI: confidence interval.
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