The Impact of Host Metabolic Factors on Treatment Outcome in Chronic Hepatitis C

Table 4

Variable associations with presence of hepatic steatosis.

	No steatosis; (𝑛=241)	Hepatic steatosis; (𝑛=113)	𝑃 values
Gender (males%)	136 (56.4)	59 (52.2)	0.457
Age ≥40 years (𝑛%)	132 (55.0)	71 (65.1)	0.075
IVDU (𝑛%)	80 (33.3)	31 (27.4)	0.265
Alcohol abuse (𝑛%)	20 (8.5)	21 (20.0)	0.003
BMI (kg/m^2)	23.6±3.5	23.6±4.8	0.988
Overweight (𝑛%)	18 (34.6)	30 (37.5)	0.736
Genotype distribution			0.721
Genotype 1	117 (49.4)	46 (43.0)
Genotype 2	15 (6.3)	8 (7.5)
Genotype 3	76 (32.1)	37 (34.6)
Genotype 4	29 (12.2)	16 (15.0)
High viral load (𝑛%)	27 (32.9)	40 (54.1)	0.008
Abnormal ALT (𝑛%)	231 (97.9)	98 (92.5)	0.015
Abnormal AST (𝑛%)	202 (89.0)	74 (79.6)	0.026
Severe inflammation (𝑛%)	5 (2.2)	12 (12.0)	<0.001
Advanced fibrosis (𝑛%)	22 (9.2)	34 (30.1)	<0.001
Cirrhosis (𝑛%)	9 (3.8)	12 (10.6)	0.011
SVR (𝑛%)	185 (76.8)	64 (56.6)	<0.001