The Role of Serum Cytokines in the Pathogenesis of Hepatic Osteodystrophy in Male Cirrhotic Patients
Table 1
Basic demographic and laboratory data* of the study population.
Parameter
Control
Cirrhosis
Cirrhosis-viral
Cirrhosis-alcoholic
Alcoholic
Number of patients (male)
17
44
27
17
15
Etiology (HBV/HCV)
—
—
20/7
—
—
Age
48.7 ± 3.8
50.8 ± 8.8
49.6 ± 9.3
50.7 ± 7.7
46.9 ± 11.0
BMI (kg/m2)
28.1 ± 3.9
26.97 ± 2.79
26.47 ± 2.47
27.78 ± 3.16
25.37 ± 3.49
Alcohol (g/day)
—
—
—
111 ± 60
122 ± 50
Cigarette
3/17†
38/44
21/27
13/17
15/15
Food
16/17
43/44
26/27
17/17
15/15
Caffeine
7/17
11/44
8/27
3/17†
11/15
AST
24 ± 2
65 ± 40
69 ± 40‡
59 ± 40‡
28 ± 36
ALP
63 ± 21
109 ± 69
84 ± 36
147 ± 90¶
96 ± 42
GGT
41 ± 12
85 ± 82
59 ± 47
126 ± 108§
117 ± 140§
Total bilirubin
1.1 ± 0.2
2.3 ± 1.9
2.2 ± 1.8†
2.6 ± 2.2†
0.9 ± 0.3
Total protein
6.7 ± 0.1
7.1 ± 2.7
6.8 ± 0.7
7.6 ± 4.3
6.5 ± 0.6
Albumin
4.2 ± 0.2
2.7 ± 0.8
2.8 ± 0.9†
2.5 ± 0.7†
3.7 ± 0.5
PT
12.8 ± 0.9
16.9 ± 2.8
17.7 ± 3.4†
17.0 ± 2.1†
12.3 ± 09
Hemoglobin
15.2 ± 0.7
12.1 ± 2.4
12.6 ± 2.6†
11.1 ± 1.8†
15.7 ± 1.2
Platelet
227000 ± 26000
132000 ± 65000a
126000 ± 64000†
142000 ± 69000†
223000 ± 66000
WBC
6400 ± 500
4146 ± 2229
4800 ± 1998†
3735 ± 2510†
8626 ± 1627
Data are presented as mean ± standard deviation. †P < 0.001 versus normal, ‡P < 0.001 versus normal, ¶P < 0.001 versus all other groups, §P < 0.001 versus control and viral cirrhosis.
