Review Article

Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review

Table 1

Classification of crypt architecture by e-CLE assessment in ulcerative colitis [6].

CLE crypt architectureDescription

(A) normalRegular arrangement and size of crypts
(B) chronic inflammationIrregular arrangement of crypts, enlarged spaces between crypts
(C) acute inflammationDilation of crypt openings, more irregular arrangement of crypts, and enlarged spaces between crypts as compared to type B
(D) acute inflammationCrypt destruction and/or crypt abscess