Establishment of a Standardized Liver Fibrosis Model with Different Pathological Stages in Rats
The pathological stage of the 5th–8th week is S2. The figure was the general appearance of liver pathology: there were evident swellings of the liver. Under the microscope, the hepatic lobular architecture was unclear, the arrangement of hepatic plate was disorganized, the hepatocytes showed vacuolar degeneration, and the hepatocytes showed necrosis in fragments. The liver sinusoid was narrowing or disappeared by compression. The fibrosis could be observed in the portal area but was localized in the lobule. HE. Bar 5200 mm.