Pantoprazole before Endoscopy in Patients with Gastroduodenal Ulcer Bleeding: Does the duration of Infusion and Ulcer Location Influence the Effects?
Table 3
Outcomes for the 175 duodenal ulcer bleeders with different durations of pantoprazole infusion compared to saline infusion.
Outcome (duodenal ulcer bleeders)
Saline
Pantoprazole all
Pantoprazole 0–4 hrs
Pantoprazole >4 hrs
Pantoprazole >6 hrs
()
()
P value
()
P value
()
P value
()
P value
Number of pts. (%)
Number of pts. (%)
Number of pts. (%)
Number of pts. (%)
Endoscopic signs of bleeding from duodenal ulcers
Active bleeding
14 (29.8%)
31 (24.2%)
0.46
19 (24.6%)
0.53
12 (23.5%)
0.48
10 (23.8%)
0.53
Nonbleeding visible vessel
7 (14.8%)
27 (21.1%)
0.36
17 (22.0%)
0.33
10 (19.6%)
0.54
9 (21.4%)
0.42
Clot
7 (14.8%)
24 (18.7%)
0.55
16 (20.8%)
0.41
8 (15.7%)
0.91
8 (19.0%)
0.60
Pigmented spot and clean base
19 (40.4%)
46 (35.9%)
0.59
25 (32.5%)
0.36
21 (0.41%)
0.94
15 (35.7%)
0.65
Urgent endoscopy
5 (10.6%)
11 (8.5%)
0.64
6 (7.8%)
0.52
5 (9.8%)
0.82
3 (7.1%)
0.54
Recurrent bleeding
9 (19.1%)
22 (17.2%)
0.76
11 (14.2%)
0.47
11 (21.5%)
0.77
10 (23.8%)
0.59
Emergency surgery
8 (17.0%)
15 (12.3%)
0.36
8 (10.4%)
0.28
7 (13.7%)
0.81
6 (14.3%)
0.72
Mortality
3 (6.3%)
7 (5.7%)
0.76
5 (6.4%)
0.98
2 (3.9%)
0.58
1 (2.3%)
0.36
P values were calculated for comparison between saline infusion group and pantoprazole infusion group patients with different durations of pantoprazole administration.
