Research Article

Bifidobacterium animalis ssp. lactis 420 Protects against Indomethacin-Induced Gastric Permeability in Rats

Table 1

Total damaged area of the rat stomach mucosa.

GroupaNMean (mm2)SDWeighted meanbWeighted SD

Control400.100.500.120.70
NSAID402.74c2.993.25c4.43
Probiotic391.91c3.122.43c5.00

aThe treatment groups were control, indomethacin-challenged group (NSAID), and a probiotic group supplemented daily with 1010 colony forming units of Bifidobacterium lactis 420 for seven days prior to indomethacin challenge.
bThe weighted values were calculated by multiplying the detected TDA values of increasing severity with 1/10, 3/10, and 6/10, respectively.
cANOVA P < 0.0001 when compared with control.