Effect of Non-Anticoagulant N-Desulfated Heparin on Basic Fibroblast Growth Factor Expression, Angiogenesis, and Metastasis of Gastric Carcinoma In Vitro and In Vivo

Table 2

bFGF expression of gastric cancer SGC-7901 cells in 0.1 mg/mL, 1 mg/mL N-desulfated heparin groups, and control group (pg/mL, 𝑥±𝑠, 𝑛=3).

Groups	12 hr	24 hr
Control group	17.724±0.173	19.690±0.111^∗
0.1 mg/mL N-desulfated heparin group	15.313±0.394^▵	13.301±0.358^▵∗
1 mg/mL N-desulfated heparin group	12.173±0.063^▵#	11.174±0.286^▵∗#

∗24 hr versus 12 hr, 𝑃<0.05; ▵different concentrations (0.1 mg/mL, 1 mg/mL) of N-desulfated heparin versus control group, 𝑃<0.05; #1 mg/mL N-desulfated heparin group versus 0.1 mg/mL N-desulfated heparin group, 𝑃<0.05.