Clinical Study
The Correlation between Microsatellite Instability and the Features of Sporadic Colorectal Cancer in the North Part of Iran
Table 1
Clinicopathological features of colorectal cancers patients according to microsatellite instability status.
| | | MSS CRC | MSI CRC | value | | | () | () | (MSI versus MSS) |
| | Age | | | 0.09 | | Mean ± SD | 61.88 ± 13.4 | 59.23 ± 16.8 | | | Median (range) | 63.5 (27–85) | 62 (31–85) | | | Gender (%) | | | 0.29 | | Male | 40 (54.1) | 14 (63.6) | | | Female | 34 (45.9) | 8 (36.4) | | | Tumor location (%) | | | 0.04* | | Proximal | 30 (40.5) | 4 (18.2) | | | Distal | 44 (59.5) | 18 (81.8) | | | Metastasis of lymph node (%) | | | 0.259 | | Yes | 46 (62.2) | 16 (72.7) | | | No | 28 (37.8) | 6 (27.3) | | | Tumor size (%) | | | 0.595 | | <20 mm | 45 (60.8) | 11 (50.0) | | | 20–50 mm | 23 (31.1) | 8 (36.4) | | | >50 mm | 6 (8.1) | 3 (13.6) | | | Tumor grade (%) | | | 0.418 | | Well differentiated | 35 ( 47.3) | 13 (59.1) | | | Moderate differentiated | 37 (50.0) | 7 (31.8) | | | Poor differentiated | 2 (2.7) | 2 (9.1) | |
|
|
MSI: microsatellite instability, MSS: microsatellite stable, CRC: colorectal cancer, SD: standard deviation, : number.
*Significant.
|
