The Association between Obesity and Colorectal Cancer

Table 1

Obesity and risk of developing colon cancer.

Study	Study type	Population	𝑁	CRC risk obese versus nonobese	Conclusion
Dai et al. 2007 [15]	Meta-analysis	International	6,458	RR 1.37 for males	Obese men have increased risk of CRC
Polednak 2008 [7]	Meta-analysis	American	153,760	RR 1.4 for males; RR 1.1 for females	Obese men have greater risk of CRC
Harriss et al. 2009 [8]	Meta-analysis	International	67,361	RR 1.24 for males; RR 1.09 for females	Higher BMI increases risk of colon cancer. Men have greater risk than women.
Pischon et al. 2006 [16]	Prospective cohort	European	368,277	RR 1.55 for males; RR 1.06 for females	Obese men have greater risk of CRC
Rapp et al. 2005 [17]	Prospective cohort	Austrian	145,000	HR 1.56 for males and colon cancer	Obese men have greater risk of CRC. Obese womens have greater risk of colon cancer relative to rectal cancer.
				HR 1.11 for females and colon cancer
				HR 1.66 for males and rectal cancer
				HR 0.66 for females and rectal cancer

RR: relative risk.
HR: hazard ratio.