Gastroenterology Research and Practice / 2012 / Article / Tab 2

Research Article

Hyperthermic Intraperitoneal Chemotherapy with Melphalan: A Summary of Clinical and Pharmacological Data in 34 Patients

Table 2

Univariate analysis of clinical factors associated with grade 4 postoperative morbidity in 34 patients treated with cytoreductive surgery and HIPEC with melphalan.

Clinical variable Grade 4 morbidity value
YesNo

Dose of melphalan0.01
 50 mg/m20
 60 mg/m20
 70 mg/m24
Number of peritonectomies<0.001
 ≤21
 >25
Number of visceral resections0.002
 ≤20
 >26
Peritoneal cancer index0.38
 ≤201
 >205
EPIC0.13
 Yes2
 No26

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