Clinical Study

Adjuvant Bidirectional Chemotherapy with Intraperitoneal Pemetrexed Combined with Intravenous Cisplatin for Diffuse Malignant Peritoneal Mesothelioma

Figure 1

Concentration times time graph of pemetrexed in peritoneal fluid and plasma from four different pharmacologic studies. The AUC ratio of peritoneal fluid to plasma was 70. Peak plasma concentration was 0.05 (+0.02) μg/mL at 30 minutes.