E. coli-Produced BMP-2 as a Chemopreventive Strategy for Colon Cancer: A Proof-of-Concept Study
Schematic layout of the pTrcHis TOPO TA expression vector (Invitrogen, Netherland) used in this study for prokaryotic expression and the strategy employed to insert the ileal-derived human BMP-2 in this vector. The same vector, but driving LacZ expression, was used as control organism.
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