Table 6: Comparison between different GI mast cell diseases [20, 24].

Cardinal symptomsNumber of mast cells/HPFSerum markers

Mastocytic enterocolitisAbdominal pain, diarrhea>20N/A
Mast cell Activation syndromeAbdominal pain, dermatographism, flushing17–23Serum tryptase
Allergic mastocytic Gastroenteritis and colitisAbdominal pain, dysmotilitysymptoms (e.g., early satiety, bloating), nocturnal awakening>40Histamine, IgE