Research Article
Parenteral Nutrition-Induced Cholestasis in Neonates: Where Does the Problem Lie?
Table 1
Demographics of patients (exposed to PN for at least 2 weeks).
| | | Control
() | Cholestasis
() | value |
| | Gender, male (%) | 37 (53.6) | 15 (83.3) | 0.023 | | Birth weight, grams, mean (SD) | 1,781 (±1013) | 1980 (±997) | 0.340 | | Gestational age, (%) | | | | | <32 + 0/7 WGA | 31 (44.9) | 8 (44.4) | 0.759s | | 32 + 0/7–36 + 6/7 WGA | 18 (26) | 4 (22.2) | | | 37 + 0/7–38 WGA | 4 (5.8) | 1 (5.6) | | | >38 WGA | 16 (23.2) | 5 (27.8) | | | Apgar < 6 at 5 min, (%) | 14 (20.3) | 4 (23.5) | 0.515† | | IUGR, (%) | 10 (14.5) | 2 (11.1) | 1.00s | | Number of episodes of sepsis, mean (SD) | 0.78 (±0.9) | 0.72 (±1.0) | 0.645 | | Top 2 GI abnormality | | | | | No. 1 | Gastroschisis (6) | Gastroschisis (2) | NA | | No. 2 | Bowel perforation (5) | NA | NA |
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PN: parenteral nutrition, IUGR: intrauterine growth restriction, NEC: necrotizing enterocolitis, GI: gastrointestinal, WGA: weeks of gestational age, sFisher’s exact test, Mann-Whitney , †Pearson chi-squared test.
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