Parenteral Nutrition-Induced Cholestasis in Neonates: Where Does the Problem Lie?
Table 2
Composition and duration of PN.
Control ()
Cholestasis ()
value
Duration of PN, days, median (IQR)
20 (15–31)
39 (24.2–53.0)
0.001
Introduction of enteral feeds DOL, median (IQR)
8.0 (3.3–19.8)
14.0 (5.5–36.5)
0.29
CH g/kg/day, median (IQR)
12.5 (10.0–13.2)
14.4 (12.5–16.2)
0.002
Lipids g/kg/day, median (IQR)
3.0 (3.0-3.0)
3.0 (3.0–3.4)
0.49
AA g/kg/day, median (IQR)
3.5 (3.0–3.5)
3.5 (3.5–4.0)
0.01
PN: parenteral nutrition, CH: carbohydrate, aa: amino acid, DOL: days of life. Statistical analysis with the Mann-Whitney test. value is statistically significant.
