Fluorescence-Guided Surgery and Fluorescence Laparoscopy for Gastrointestinal Cancers in Clinically-Relevant Mouse Models
Figure 2
(a) Fluorescence laparoscopy with fluorophore-conjugated antibodies. Images under fluorescence and bright field laparoscopy visualized the primary tumor in the body of the pancreas. The two images on the left are positive control images taken with the Olympus OV-100 small animal imaging system for comparison with laparoscopic images on the right under fluorescence (top) and bright field (bottom). The primary pancreatic tumor was more easily detected under fluorescence laparoscopy (FL) compared to bright field laparoscopy (BL) [2]. (b) Use of fluorescence laparoscopy to identify primary and metastatic lesions. The center image is a positive control OV-100 image for comparison with BL and FL. The surrounding images, labeled 1–6, are representative FL images of primary and metastatic pancreatic tumor lesions. The numbers in the upper left corner of each picture correspond to the numbered lesion in the center OV-100 image [2].
