Review Article
Gastroesophageal Reflux Disease Relief in Patients Treated with Rabeprazole 20 mg versus Omeprazole 20 mg: A Meta-Analysis
Table 1
Characteristics of the included studies.
| Source | Study design | Region | Identification of relief | Number of patients | Mean ages (years) | Daily dosage | Duration | Male | Female | RAB 20 mg |
OME 20 mg |
| Dekkers et al. (1999) [7] | DB, RCT | Europe, 27 centers | Endoscopy, heartburn symptom | 126 | 76 | 53 | 100 | 102 | 8 weeks | Delchier et al. (2000) [12] | DB, RCT | Europe, 50 centers | Endoscopy, heartburn symptom | 87 | 120 | 54 | 104 | 103 | 8 weeks | Adachi et al. (2003) [13] | DB, RCT | Japan, 6 centers | Endoscopy, heartburn symptom | 30 | 30 | 66 | 30 | 30 | 8 weeks | Pace et al. (2005) [14] | DB, RCT | Italy, 71 centers | Endoscopy, heartburn symptom | 374 | 175 | 47 | 277 | 272 | 8 weeks | Bytzer et al. (2006) [15] | DB, RCT | Europe, 49 centers | Heartburn symptom | 374 | 343 | 51 | 358 | 359 | 1 week | Pilotto et al. (2007) [16] | Unblind, RCT | Italy, 1 center | Endoscopy, heartburn symptom | 81 | 79 | 77 | 80 | 80 | 8 weeks |
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DB: double-blind; RCT: randomized clinical trial; RAB: rabeprazole; OME: omeprazole.
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