Gastroenterology Research and Practice / 2013 / Article / Tab 1

Review Article

Functional Dyspepsia in Review: Pathophysiology and Challenges in the Diagnosis and Management due to Coexisting Gastroesophageal Reflux Disease and Irritable Bowel Syndrome

Table 1

Comparison of Rome II and Rome III.

Rome IIRome III

Duration of symptoms12 weeks12 weeks

Time period preceding diagnosis12 months6 months

Bothersome postprandial fullness
Early satiation

Location of symptomsCentered in the upper abdomenEpigastric

Need to rule out organic causesYesYes

Other exclusionsNot relieved by defecation
Not associated with change in stool frequency or form

Ulcer like
 Pain in the upper abdomen
Postprandial distress syndrome
 Bothersome postprandial fullness after meals
 Early satiation before finishing a regular meal
(feature/location of symptoms)
Dysmotility like
 An unpleasant nonpainful sensation
 centered in upper abdomen
Epigastric pain syndrome
 Pain or burning at epigastrium
 Pain of at least moderate severity
 Pain is intermittent, not relieved by defecation
 Pain not caused by gallbladder or sphincter of
 Oddis dysfunction pain
 Symptoms do not fit in the above

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