Review Article

Combination Therapy of Ursodeoxycholic Acid and Corticosteroids for Primary Biliary Cirrhosis with Features of Autoimmune Hepatitis: A Meta-Analysis

Table 1

Criteria used to grade the quality of RCTs: the Jadad scores.

Each study was given one point for each “yes” and 0 points for each “no” in response to each of the following questions.

(1) Was the study described as randomized using the words “randomly”, “random”, or “randomization”?
(a) An additional point was given if the method of randomization was described and was appropriate (e.g., table of random numbers, computer generated).
(b) A point was deducted if the method of randomization was inappropriate (e.g., patients allocated alternately, by birth date, or by hospital number).
(2) Was the study described as “double blind”?
(a) A point was given if the method of blinding was described and it was appropriate (e.g., identical placebo).
(b) An additional point was deducted if the method of blinding was inappropriate (e.g., comparing placebo tablet with injection).
(3) Was there a description of the patients who withdrew or dropped out?
The maximum number of points was 5.