Figure 3: Effect of repeated administration of ghrelin to GERD rats. (a) Body weight and (b) daily food intake in sham-operated and GERD rats. Exogenous ghrelin (3 nmol/rat/day) was intravenously administered to rats once daily. Sham-operated rats and control group of GERD rats were administered saline. There were no significant differences in body weight or food intake between the saline-administered and ghrelin-administered groups in GERD rats. *, **, and *** , 0.01, and 0.001 versus sham-operated rats on each day.