Review Article
Current Advances in the Diagnosis and Treatment of Nonerosive Reflux Disease
Table 1
Classification of patients with reflux symptoms.
| Classification | Distal esophageal acid exposure | Symptom correlation | Symptom response to PPI |
| Erosive esophagitis | Increased | (+) | Good | Barrett’s esophagus | Increased | (+) | Good | NERD | | | | Acid reflux related | Increased | (+) | Good | Weakly acid related | Not increased | (+) | Moderate* | Nonacid related | Not increased | (+) | Poor* | Functional heartburn | Not increased | (−) | Poor |
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Not well investigated.
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