Gastroenterology Research and Practice / 2013 / Article / Tab 1

Review Article

Current Advances in the Diagnosis and Treatment of Nonerosive Reflux Disease

Table 1

Classification of patients with reflux symptoms.

ClassificationDistal esophageal acid exposureSymptom correlationSymptom response to PPI

Erosive esophagitisIncreased(+)Good
Barrett’s esophagusIncreased(+)Good
NERD
 Acid reflux relatedIncreased(+)Good
 Weakly acid relatedNot increased(+)Moderate*
 Nonacid relatedNot increased(+)Poor*
Functional heartburnNot increased(−)Poor

Not well investigated.

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