Current Advances in the Diagnosis and Treatment of Nonerosive Reflux Disease
Table 1
Classification of patients with reflux symptoms.
Classification
Distal esophageal acid exposure
Symptom correlation
Symptom response to PPI
Erosive esophagitis
Increased
(+)
Good
Barrett’s esophagus
Increased
(+)
Good
NERD
Acid reflux related
Increased
(+)
Good
Weakly acid related
Not increased
(+)
Moderate*
Nonacid related
Not increased
(+)
Poor*
Functional heartburn
Not increased
(−)
Poor
Not well investigated.
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