Gastroenterology Research and Practice / 2013 / Article / Tab 2

Review Article

Current Advances in the Diagnosis and Treatment of Nonerosive Reflux Disease

Table 2

Clinical and physiological characteristics between patients with NERD and erosive esophagitis.

CharacteristicsNERD Erosive esophagitis

GenderFemaleNo difference
Age (yr)40–5050–60
Smoking (%)15–2310–23
Alcohol (%)8–596–64
Symptom duration (yr)1–51–5
Hiatal hernia (%)20–2939–56
Helicobacter pylori (+) (%)34–4120–26
Resting LES pressureNormalNormal to low
Abnormal esophageal motilityMildModerate to severe
Esophageal acid clearanceNormal Abnormal
Distal esophageal pH (<4) (% of time)Slightly increasedModerately increased

NERD: nonerosive reflux disease; mild: ineffective esophageal motility alone; moderate to severe: ineffective esophageal motility and impaired bolus clearance.

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