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Gastroenterology Research and Practice
Volume 2013, Article ID 829040, 12 pages
http://dx.doi.org/10.1155/2013/829040
Review Article

Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age

Unit of Paediatric Gastroenterology, Digestive Endoscopy, Hepatology, and Care of Children with Liver Transplantation, Department of Women’s and Children’s Health, University Hospital of Padova, Via Giustiniani 3, 35128 Padova, Italy

Received 30 August 2013; Revised 27 October 2013; Accepted 20 November 2013

Academic Editor: Andrew S. Day

Copyright © 2013 Marco Gasparetto and Graziella Guariso. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [41 citations]

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  • Jeremy N. Myers, Michael W. Schäffer, Olga Y. Korolkova, Amanda D. Williams, Pandu R. Gangula, and Amosy E. MʼKoma, “Implications of the Colonic Deposition of Free Hemoglobin-α Chain,” Inflammatory Bowel Diseases, vol. 20, no. 9, pp. 1530–1547, 2014. View at Publisher · View at Google Scholar
  • Kewir D. Nyuyki, and Quentin J. Pittman, “Toward a better understanding of the central consequences of intestinal inflammation,” Annals of the New York Academy of Sciences, vol. 1351, no. 1, pp. 149–154, 2015. View at Publisher · View at Google Scholar
  • Jie Yin, Miaomiao Wu, Jielin Duan, Gang Liu, Zhijie Cui, Jie Zheng, Shuai Chen, Wenkai Ren, Jinping Deng, Xiangwen Tan, Naif Abdullah Al-Dhabi, Veeramuthu Duraipandiyan, Peng Liao, Tiejun Li, and Yin Yulong, “Pyrrolidine Dithiocarbamate Inhibits NF-KappaB Activation and Upregulates the Expression of Gpx1, Gpx4, Occludin, and ZO-1 in DSS-Induced Colitis,” Applied Biochemistry and Biotechnology, 2015. View at Publisher · View at Google Scholar
  • Sameer Lapsia, Siva Koganti, Salvatore Spadaro, Ramona Rajapakse, Anupama Chawla, and Sumita Bhaduri-McIntosh, “Anti-TNFα therapy for inflammatory bowel diseases is associated with Epstein-Barr virus lytic activation,” Journal of Medical Virology, 2015. View at Publisher · View at Google Scholar
  • James W. Varni, James P. Franciosi, Robert J. Shulman, Shehzad Saeed, Samuel Nurko, Deborah A. Neigut, Cristiane B. Bendo, Ashish S. Patel, Mariella M. Self, Miguel Saps, George M. Zacur, Jolanda Denham, Chelsea Vaughan Dark, and John F. Pohl, “PedsQL Gastrointestinal Symptoms Scales and Gastrointestinal Worry Scales in Pediatric Patients with Inflammatory Bowel Disease in Comparison with Healthy Controls,” Inflammatory Bowel Diseases, vol. 21, no. 5, pp. 1115–1124, 2015. View at Publisher · View at Google Scholar
  • Andrea Buda, Sonia Facchin, Elisa Dassie, Elisabetta Casarin, Mark A. Jepson, Helmut Neumann, Giorgia Hatem, Stefano Realdon, Renata D'Inca, Giacomo Carlo Sturniolo, and Margherita Morpurgo, “Detection of a fluorescent-labeled avidin-nucleic acid nanoassembly by confocal laser endomicroscopy in the microvasculature of chronically inflamed i,” International Journal Of Nanomedicine, vol. 10, pp. 399–408, 2015. View at Publisher · View at Google Scholar
  • Jill M. Plevinsky, Rachel N. Greenley, and Laurie N. Fishman, “Self-management in patients with inflammatory bowel disease: Strategies, outcomes, and integration into clinical care,” Clinical and Experimental Gastroenterology, vol. 9, pp. 259–267, 2016. View at Publisher · View at Google Scholar
  • Pieta Lehtinen, Kari Pasanen, Kaija-Leena Kolho, and Anssi Auvinen, “Incidence of Pediatric Inflammatory Bowel Disease in Finland,” Journal of Pediatric Gastroenterology and Nutrition, vol. 63, no. 1, pp. 65–70, 2016. View at Publisher · View at Google Scholar
  • Céline Dubron, Freddy Avni, Nathalie Boutry, Dominique Turck, Alain Duhamel, and Elisa Amzallag-bellenger, “Prospective evaluation of free-breathing diffusion-weighted imaging for the detection of inflammatory bowel disease with MR enterography in childhood population,” The British Journal of Radiology, vol. 89, no. 1060, pp. 20150840, 2016. View at Publisher · View at Google Scholar
  • Hubert Zatorski, Mateusz Marynowski, and Jakub Fichna, “Is insulin-like growth factor 1 (IGF-1) system an attractive target inflammatory bowel diseases? Benefits and limitation of potential therapy,” Pharmacological Reports, 2016. View at Publisher · View at Google Scholar
  • James W. Varni, Robert J. Shulman, Mariella M. Self, Shehzad A. Saeed, Ashish S. Patel, Samuel Nurko, Deborah A. Neigut, Miguel Saps, James P. Franciosi, Jolanda M. Denham, George M. Zacur, Chelsea V. Dark, Cristiane B. Bendo, and John F. Pohl, “Gastrointestinal Symptoms Predictors of Health-Related Quality of Life in Patients With Inflammatory Bowel Disease,” Journal of Pediatric Gastroenterology and Nutrition, vol. 63, no. 6, pp. e186–e192, 2016. View at Publisher · View at Google Scholar
  • Jeannie S. Huang, Laura Terrones, Alan N. Simmons, Walter Kaye, and Irina Strigo, “Pilot Study of Functional Magnetic Resonance Imaging Responses to Somatic Pain Stimuli in Youth With Functional and Inflammatory Gastrointestinal Disease,” Journal of Pediatric Gastroenterology and Nutrition, vol. 63, no. 5, pp. 500–507, 2016. View at Publisher · View at Google Scholar
  • Máire A. Conrad, Ronen E. Stein, Elizabeth C. Maxwell, Lindsey Albenberg, Robert N. Baldassano, Noor Dawany, Andrew B. Grossman, Petar Mamula, David A. Piccoli, and Judith R. Kelsen, “Vedolizumab Therapy in Severe Pediatric Inflammatory Bowel Disease,” Inflammatory Bowel Diseases, vol. 22, no. 10, pp. 2425–2431, 2016. View at Publisher · View at Google Scholar
  • Aoife Kilcoyne, Jess L. Kaplan, and Michael S. Gee, “Inflammatory bowel disease imaging: current practice and future directions,” World Journal Of Gastroenterology, vol. 22, no. 3, pp. 917–932, 2016. View at Publisher · View at Google Scholar
  • Gang Liu, Qian Jiang, Shuai Chen, Jun Fang, Wenkai Ren, Jie Yin, Kang Yao, and Yulong Yin, “Melatonin alters amino acid metabolism and inflammatory responses in colitis mice,” Amino Acids, 2017. View at Publisher · View at Google Scholar
  • Jorge Amil-Dias, Sanja Kolacek, Dan Turner, Anders Pærregaard, Risto Rintala, Nadeem A. Afzal, Katarzyna Karolewska-Bochenek, Jiri Bronsky, Sonny Chong, John Fell, Iva Hojsak, Jean-Pierre Hugot, Sibylle Koletzko, Devinder Kumar, Izabella Lazowska-Przeorek, Craig Lillehei, Paolo Lionetti, Javier Martin-de-Carpi, Mikko Pakarinen, Frank M. Ruemmele, Ron Shaoul, Christine Spray, Annamaria Staiano, Ian Sugarman, David C. Wilson, Harland Winter, and Kaija-Leena Kolho, “Surgical Management of Crohn Disease in Children,” Journal of Pediatric Gastroenterology and Nutrition, vol. 64, no. 5, pp. 818–835, 2017. View at Publisher · View at Google Scholar
  • J.K. Yamamoto-Furusho, F. Bosques-Padilla, P. Daffra, J.A. De Paula, J. Etchevers, M.T. Galiano, P. Ibañez, F. Juliao, P.G. Kotze, J.M. Marroquín de la Garza, R. Monreal Robles, J.L. Rocha, F. Steinwurz, R. Vázquez-Frías, G. Veitia, and C. Zaltman, “Special situations in inflammatory bowel disease: First Latin American consensus of the Pan American Crohn's and Colitis Organisation (PANCCO) (Second part),” Revista de Gastroenterología de México (English Edition), 2017. View at Publisher · View at Google Scholar
  • J.K. Yamamoto-Furusho, F. Bosques-Padilla, P. Daffra, J. De-Paula, J. Etchevers, M.T. Galiano, P. Ibañez, F. Juliao, P. Kotze, J.M. Marroquín de la Garza, R. Monreal Robles, J.L. Rocha, F. Steinwurz, R. Vázquez-Frías, G. Veitia, and C. Zaltman, “Situaciones especiales en la enfermedad inflamatoria intestinal: primer consenso latinoamericano de la Pan American Crohn's and Colitis Organisation (PANCCO),” Revista de Gastroenterología de México, 2017. View at Publisher · View at Google Scholar
  • Haihao Sun, Richard Vesely, Kerry Jo Lee, Agnes Klein, Mutsuhiro Ikima, and Andrew E. Mulberg, “Pediatric Crohn Disease Clinical Outcome Assessments and Biomarkers,” Journal of Pediatric Gastroenterology and Nutrition, vol. 64, no. 3, pp. 368–372, 2017. View at Publisher · View at Google Scholar
  • Domenico Corica, and Claudio Romano, “Biological Therapy in Pediatric Inflammatory Bowel Disease,” Journal of Clinical Gastroenterology, vol. 51, no. 2, pp. 100–110, 2017. View at Publisher · View at Google Scholar
  • Aodhnait S. Fahy, D. Dean Potter, William A. Faubion, Jeanne Tung, Anupama Ravi, and Yannis Reissis, “Colectomy in refractory Crohn's colitis improves nutrition and reduces steroid use,” Journal of Pediatric Surgery, vol. 52, no. 11, pp. 1769–1775, 2017. View at Publisher · View at Google Scholar
  • Olga Vyacheslavovna Shcherbakova, Shumilov, and Razumovskiy, “Crohn’s disease in children: Epidemiology, classification, diagnostics, indications for surgery,” Pediatriya - Zhurnal im G.N. Speranskogo, vol. 96, no. 6, pp. 157–165, 2017. View at Publisher · View at Google Scholar
  • Amy L. Lightner, Chung Sang Tse, D. Dean Potter, and Christopher Moir, “Postoperative Outcomes in Vedolizumab-Treated Pediatric Patients Undergoing Abdominal Operations for Inflammatory Bowel Disease,” Journal of Pediatric Surgery, 2017. View at Publisher · View at Google Scholar
  • Sanja Kolaček, and Iva Hojsak, “Chronic infl ammatory bowel diseases in children - Novelties in the etiology, phenotype, diagnosis and treatment,” Paediatria Croatica, vol. 61, no. 1, pp. 10–25, 2017. View at Publisher · View at Google Scholar
  • Gang Liu, Jun Fang, Chien-An Andy Hu, Jie Yin, Hengjia Ni, Wenkai Ren, Veeramuthu Duraipandiyan, Naif Abdullah Al-Dhabi, Yulong Yin, Lei Yu, and Shuai Chen, “Methionine restriction on oxidative stress and immune response in dss-induced colitis mice,” Oncotarget, vol. 8, no. 27, pp. 44511–44520, 2017. View at Publisher · View at Google Scholar
  • Halima E. Al-Jowder, Khadija A. Matrook, Hasan M. Isa, Afaf M. Mohamed, and Haya H. Althawadi, “Pediatric crohn’s disease in Bahrain,” Oman Medical Journal, vol. 33, no. 4, pp. 299–308, 2018. View at Publisher · View at Google Scholar
  • Huaijun Wang, Jean-Marc Hyvelin, Stephen A. Felt, Ismayil Guracar, Jose G. Vilches-Moure, Samir Cherkaoui, Thierry Bettinger, Lu Tian, Amelie M. Lutz, and Jürgen K. Willmann, “US Molecular Imaging of Acute Ileitis: Anti-Inflammatory Treatment Response Monitored with Targeted Microbubbles in a Preclinical Model,” Radiology, pp. 172600, 2018. View at Publisher · View at Google Scholar
  • Anita Afzali, and Seymour Katz, “Inflammatory Bowel Disease in the Baby to Baby Boomer: Pediatric and Elderly Onset of IBD,” Current Treatment Options in Gastroenterology, vol. 16, no. 3, pp. 289–305, 2018. View at Publisher · View at Google Scholar
  • Violeta Balbas-Martinez, Leire Ruiz-Cerdá, Itziar Irurzun-Arana, Ignacio González-García, An Vermeulen, José David Gómez-Mantilla, and Iñaki F. Trocóniz, “A systems pharmacology model for inflammatory bowel disease,” Plos One, vol. 13, no. 3, pp. e0192949, 2018. View at Publisher · View at Google Scholar
  • Kirsty M Hooper, Peter G Barlow, Paul Henderson, and Craig Stevens, “Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease,” Inflammatory Bowel Diseases, vol. 25, no. 4, pp. 661–671, 2018. View at Publisher · View at Google Scholar
  • Lien Tran, and Kathleen Mulligan, “A Systematic Review of Self-Management Interventions for Children and Adolescents With Inflammatory Bowel Disease,” Inflammatory Bowel Diseases, 2018. View at Publisher · View at Google Scholar
  • Shuai Chen, Meiwei Wang, Lanmei Yin, Wenkai Ren, Peng Bin, Yaoyao Xia, Gang Liu, Huansheng Yang, Bie Tan, and Yulong Yin, “Effects of dietary tryptophan supplementation in the acetic acid-induced colitis mouse model,” Food & Function, 2018. View at Publisher · View at Google Scholar
  • Amy K. Schaefer, James E. Melnyk, Zhaoping He, Fernando Del Rosario, and Catherine L. Grimes, “Pathogen- and Microbial- Associated Molecular Patterns (PAMPs/MAMPs) and the Innate Immune Response in Crohn’s Disease,” Immunity and Inflammation in Health and Disease, pp. 175–187, 2018. View at Publisher · View at Google Scholar
  • Dario Dilillo, Gian Vincenzo Zuccotti, Erica Galli, Fabio Meneghin, Alessandra Dell’Era, Francesca Penagini, Giacomo Colella, Peter Lewindon, Stefania Carmagnola, Elisa Farina, Sandro Ardizzone, and Giovanni Maconi, “Noninvasive testing in the management of children with suspected inflammatory bowel disease,” Scandinavian Journal of Gastroenterology, pp. 1–6, 2019. View at Publisher · View at Google Scholar
  • Gehan El-Akabawy, and Neveen M. El-Sherif, “Zeaxanthin exerts protective effects on acetic acid-induced colitis in rats via modulation of pro-inflammatory cytokines and oxidative stress,” Biomedicine & Pharmacotherapy, vol. 111, pp. 841–851, 2019. View at Publisher · View at Google Scholar
  • Amy L. Lightner, Nicholas P. McKenna, Ahmad Alsughayer, Edward V. Loftus Jr, Laura E. Raffals, William A. Faubion, and Christopher Moir, “Anti-TNF Biologic Therapy Does Not Increase Postoperative Morbidity in Pediatric Crohn's Patients,” Journal of Pediatric Surgery, 2019. View at Publisher · View at Google Scholar
  • Faith D. Ihekweazu, Tatiana Y. Fofanova, Karen Queliza, Dorottya Nagy-Szakal, Christopher J. Stewart, Melinda A. Engevik, Kristina G. Hulten, Nina Tatevian, David Y. Graham, James Versalovic, Joseph F. Petrosino, and Richard Kellermayer, “ Bacteroides ovatus ATCC 8483 monotherapy is superior to traditional fecal transplant and multi-strain bacteriotherapy in a murine colitis model ,” Gut Microbes, pp. 1–17, 2019. View at Publisher · View at Google Scholar
  • Judith Kraiczy, and Matthias Zilbauer, “Intestinal Epithelial Organoids as Tools to Study Epigenetics in Gut Health and Disease,” Stem Cells International, vol. 2019, pp. 1–7, 2019. View at Publisher · View at Google Scholar
  • Heather Armstrong, Misagh Alipour, Rosica Valcheva, Michael Bording-Jorgensen, Juan Jovel, Deenaz Zaidi, Prachi Shah, Yuefei Lou, Cory Ebeling, Andrew L. Mason, Dawson Lafleur, Jeremy Jerasi, Gane K.-S. Wong, Karen Madsen, Matthew W. Carroll, Hien Q. Huynh, Levinus A. Dieleman, and Eytan Wine, “Host immunoglobulin G selectively identifies pathobionts in pediatric inflammatory bowel diseases,” Microbiome, vol. 7, no. 1, 2019. View at Publisher · View at Google Scholar
  • Avelino Luiz Rodrigues, and Fernando Pardini, “Psychological Well-Being And Quality Of Life In The Clinical Approach In Crohn’S Disease,” Arquivos de Gastroenterologia, vol. 56, no. 2, pp. 111–112, 2019. View at Publisher · View at Google Scholar
  • Daniela Migliarese Isaac, and Eytan Wine, “Overview of Pediatric Crohn Disease,” Reference Module in Biomedical Sciences, 2019. View at Publisher · View at Google Scholar