Table of Contents Author Guidelines Submit a Manuscript
Gastroenterology Research and Practice
Volume 2013, Article ID 915463, 7 pages
http://dx.doi.org/10.1155/2013/915463
Clinical Study

Is Occult Obscure Gastrointestinal Bleeding a Definite Indication for Capsule Endoscopy? A Retrospective Analysis of Diagnostic Yield in Patients with Occult versus Overt Bleeding

1Department of Gastroenterology and Metabolism, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan
2Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan

Received 22 July 2013; Revised 17 September 2013; Accepted 17 September 2013

Academic Editor: Paolo Gionchetti

Copyright © 2013 Ikue Watari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Sidhu, D. S. Sanders, A. J. Morris, and M. E. McAlindon, “Guidelines on small bowel enteroscopy and capsule endoscopy in adults,” Gut, vol. 57, no. 1, pp. 125–136, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. I. M. Gralned, “Obscure-overt gastrointestinal bleeding,” Gastroenterology, vol. 128, no. 5, pp. 1424–1430, 2005. View at Publisher · View at Google Scholar
  3. G. S. Raju, L. Gerson, A. Das, and B. Lewis, “American Gastroenterological Association (AGA) Institute technical review on obscure gastrointestinal bleeding,” Gastroenterology, vol. 133, no. 5, pp. 1697–1717, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. F. J. Moawad, G. R. Veerappan, and R. K. H. Wong, “Small bowel is the primary source of obscure gastrointestinal bleeding,” Gastroenterology, vol. 135, no. 3, p. 1016, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. J. A. Leighton, J. Goldstein, W. Hirota et al., “Obscure gastrointestinal bleeding,” Gastrointestinal Endoscopy, vol. 58, no. 5, pp. 650–655, 2003. View at Publisher · View at Google Scholar
  6. “American Gastroenterological Association Medical Position Statement: evaluation and management of occult and obscure gastrointestinal bleeding,” Gastroenterology, vol. 118, no. 1, pp. 197–200, 2000. View at Scopus
  7. S. L. Triester, J. A. Leighton, G. I. Leontiadis et al., “A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding,” The American Journal of Gastroenterology, vol. 100, no. 11, pp. 2407–2418, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. K. Das, R. Sarkar, J. Dasgupta et al., “Obscure GI bleeding in the tropics: impact of introduction of double-balloon and capsule endoscopies on outcome,” Gastrointestinal Endoscopy, vol. 72, no. 2, pp. 292–300, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. C. Calabrese, G. Liguori, P. Gionchetti et al., “Obscure gastrointestinal bleeding: single centre experience of capsule endoscopy,” Internal and Emergency Medicine, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. D. Cave, P. Legnani, R. de Franchis, and B. S. Lewis, “ICCE consensus for capsule retention,” Endoscopy, vol. 37, no. 10, pp. 1065–1067, 2005. View at Publisher · View at Google Scholar · View at Scopus
  11. G. R. Zuckerman, C. Prakash, M. P. Askin, and B. S. Lewis, “AGA technical review on the evaluation and management of occult and obscure gastrointestinal bleeding,” Gastroenterology, vol. 118, no. 1, pp. 201–221, 2000. View at Google Scholar · View at Scopus
  12. M. Nakano, S. Oka, S. Tanaka et al., “Clinical usefulness of classification by transabdominal ultrasonography for detection of small-bowel stricture,” Scandinavian Journal of Gastroenterology, vol. 48, no. 9, pp. 1041–1047, 2013. View at Publisher · View at Google Scholar
  13. G. Iddan, G. Meron, A. Glukhovsky, and P. Swain, “Wireless capsule endoscopy,” Nature, vol. 405, no. 6785, pp. 417–418, 2000. View at Google Scholar · View at Scopus
  14. H. Yamamoto, Y. Sekine, Y. Sato et al., “Total enteroscopy with a nonsurgical steerable double-balloon method,” Gastrointestinal Endoscopy, vol. 53, no. 2, pp. 216–220, 2001. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Yamamoto, Y. Sekine, Y. Sato et al., “Clinical evaluation of a newly developed single-balloon enteroscope,” Gastrointestinal Endoscopy, vol. 68, no. 6, pp. 1112–1116, 2008. View at Publisher · View at Google Scholar
  16. S. Tanaka, K. Mitsui, Y. Yamada et al., “Diagnostic yield of double-balloon endoscopy in patients with obscure GI bleeding,” Gastrointestinal Endoscopy, vol. 68, no. 4, pp. 683–691, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. P. Hindryckx, T. Botelberge, M. de Vos, and D. de Looze, “Clinical impact of capsule endoscopy on further strategy and long-term clinical outcome in patients with obscure bleeding,” Gastrointestinal Endoscopy, vol. 68, no. 1, pp. 98–104, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. B. H. Jones, D. E. Fleischer, V. K. Sharma et al., “Yield of repeat wireless video capsule endoscopy in patients with obscure gastrointestinal bleeding,” The American Journal of Gastroenterology, vol. 100, no. 5, pp. 1058–1064, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. L. H. Chen, W. G. Chen, H. J. Cao et al., “Double-balloon enteroscopy for obscure gastrointestinal bleeding: a single center experience in China,” World Journal of Gastroenterology, vol. 16, no. 13, pp. 1655–1659, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. B. L. Zhang, Y. H. Fang, C. X. Chen, Y. M. Li, and Z. Xiang, “Single-center experience of 309 consecutive patients with obscure gastrointestinal bleeding,” World Journal of Gastroenterology, vol. 15, no. 45, pp. 5740–5745, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Fujimori, T. Seo, K. Gudis et al., “Diagnosis and treatment of obscure gastrointestinal bleeding using combined capsule endoscopy and double balloon endoscopy: 1-year follow-up study,” Endoscopy, vol. 39, no. 12, pp. 1053–1058, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. H. Endo, N. Matsuhashi, M. Inamori et al., “Rebleeding rate after interventional therapy directed by capsule endoscopy in patients with obscure gastrointestinal bleeding,” BMC Gastroenterology, vol. 8, article 12, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. N. Manabe, S. Tanaka, A. Fukumoto et al., “Double-balloon enteroscopy in patients with GI bleeding of obscure origin,” Gastrointestinal Endoscopy, vol. 64, no. 1, pp. 135–140, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. B. Sun, E. Rajan, S. Cheng et al., “Diagnostic yield and therapeutic impact of double-balloon enteroscopy in a large cohort of patients with obscure gastrointestinal bleeding,” The American Journal of Gastroenterology, vol. 101, no. 9, pp. 2011–2015, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. E. Redondo-Cerezo, G. P. Pérez-Vigara, A. P. Pérez-Sola et al., “Diagnostic yield and impact of capsule endoscopy on management of patients with gastrointestinal bleeding of obscure origin,” Digestive Diseases and Science, vol. 52, no. 5, pp. 1376–1381, 2007. View at Publisher · View at Google Scholar
  26. M. Pennazio, R. Santucci, E. Rondonotti et al., “Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases,” Gastroenterology, vol. 126, no. 3, pp. 643–653, 2004. View at Publisher · View at Google Scholar · View at Scopus
  27. M. K. Goenka, S. Majumder, S. Kumar, P. K. Sethy, and U. Goenka, “Single center experience of capsule endoscopy in patients with obscure gastrointestinal bleeding,” World Journal of Gastroenterology, vol. 17, no. 6, pp. 774–778, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. E. J. Carey, J. A. Leighton, R. I. Heigh et al., “A single-center experience of 260 consecutive patients undergoing capsule endoscopy for obscure gastrointestinal bleeding,” The American Journal of Gastroenterology, vol. 102, no. 1, pp. 89–95, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. E. Ben Soussan, M. Antonietti, S. Hervé et al., “Diagnostic yield and therapeutic implications of capsule endoscopy in obscure gastrointestinal bleeding,” Gastroenterologie Clinique et Biologique, vol. 28, no. 11, pp. 1068–1073, 2004. View at Google Scholar · View at Scopus
  30. R. Gupta, S. Lakhtakia, M. Tandan et al., “Capsule endoscopy in obscure gastrointestinal bleeding—an Indian experience,” Indian Journal of Gastroenterology, vol. 25, no. 4, pp. 188–190, 2006. View at Google Scholar · View at Scopus
  31. A. Fukumoto, S. Tanaka, T. Shishido, Y. Takemura, S. Oka, and K. Chayama, “Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease,” Gastrointestinal Endoscopy, vol. 69, no. 4, pp. 857–865, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. T. Shishido, S. Oka, S. Tanaka et al., “Outcome of patients who have undergone total enteroscopy for obscure gastrointestinal bleeding,” World Journal of Gastroenterology, vol. 18, no. 7, pp. 666–672, 2012. View at Publisher · View at Google Scholar · View at Scopus
  33. N. Ohmiya, T. Yano, H. Yamamoto et al., “Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy,” Gastrointestinal Endoscopy, vol. 66, no. 3, pp. S72–S77, 2007. View at Publisher · View at Google Scholar · View at Scopus
  34. A. Yamada, H. Watabe, Y. Yamaji, H. Yoshida, M. Omata, and K. Koike, “Incidence of small intestinal lesions in patients with iron deficiency anemia,” Hepato-Gastroenterology, vol. 58, no. 109, pp. 1240–1243, 2011. View at Publisher · View at Google Scholar · View at Scopus
  35. P. Apostolopoulos, C. Liatsos, I. M. Gralnek et al., “The role of wireless capsule endoscopy in investigating unexplained iron deficiency anemia after negative endoscopic evaluation of the upper and lower gastrointestinal tract,” Endoscopy, vol. 38, no. 11, pp. 1127–1132, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. P. Apostolopoulos, C. Liatsos, I. M. Gralnek et al., “Evaluation of capsule endoscopy in active, mild-to-moderate, overt, obscure GI bleeding,” Gastrointestinal Endoscopy, vol. 66, no. 6, pp. 1174–1181, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. Z. Z. Ge, H. Y. Chen, Y. J. Gao, Y. B. Hu, and S. D. Xiao, “Best candidates for capsule endoscopy for obscure gastrointestinal bleeding,” Journal of Gastroenterology and Hepatology, vol. 22, no. 12, pp. 2076–2080, 2007. View at Publisher · View at Google Scholar
  38. M. Esaki, T. Matsumoto, S. Yada et al., “Factors associated with the clinical impact of capsule endoscopy in patients with overt obscure gastrointestinal bleeding,” Digestive Diseases and Sciences, vol. 55, no. 8, pp. 2294–2301, 2010. View at Publisher · View at Google Scholar · View at Scopus
  39. G. Bresci, G. Parisi, M. Bertoni, E. Tumino, and A. Capria, “The role of video capsule endoscopy for evaluating obscure gastrointestinal bleeding: usefulness of early use,” Journal of Gastroenterology, vol. 40, no. 3, pp. 256–259, 2005. View at Publisher · View at Google Scholar · View at Scopus
  40. J. Pohl, A. May, T. Rabenstein, O. Pech, and C. Ell, “Computed virtual chromoendoscopy: a new tool for enhancing tissue surface structures,” Endoscopy, vol. 39, no. 1, pp. 80–83, 2007. View at Publisher · View at Google Scholar · View at Scopus
  41. H. Imagawa, S. Oka, S. Tanaka et al., “Improved visibility of lesions of the small intestine via capsule endoscopy with computed virtual chromoendoscopy,” Gastrointestinal Endoscopy, vol. 73, no. 2, pp. 299–306, 2011. View at Publisher · View at Google Scholar · View at Scopus
  42. H. Imagawa, S. Oka, S. Tanaka et al., “Improved detectability of small-bowel lesions via capsule endoscopy with computed virtual chromoendoscopy: a pilot study,” Scandinavian Journal of Gastroenterology, vol. 46, no. 9, pp. 1133–1137, 2011. View at Publisher · View at Google Scholar · View at Scopus