VAWCM-Instillation Improves Delayed Primary Fascial Closure of Open Septic Abdomen
Table 2
The comparison of clinical outcomes between the irrigation and control groups.
Outcome
Pooled ()
Irrigation ()
Control ()
Mortality before abdominal closurea, (%)
32 (23.9)
18 (24.6)
14 (23.0)
0.817
Primary fascial closure, (%)
71 (53.0)
46 (63.0)
25 (41.0)
0.011
Primary fascial closure in the survivalsb, /total survivals (%)
71/102 (69.6)
46/55 (83.6)
25/47 (53.2)
0.001
Time to primary fascial closure, days (range)
25 (11–42)
23 (11–34)
28 (15–42)
0.003
Hospital LOS in the survivalsc, days (range)
41 (19–88)
39 (19–88)
44 (27–79)
0.022
Hospital LOS in the survivalsc with fascial closure, days (range)
34 (19–53)
33 (19–44)
37 (27–53)
0.001
Complications
Intra-abdominal abscess, (%)
31 (23.1)
12 (16.4)
19 (31.1)
0.044
Postoperative fistula, (%)
27 (20.1)
11 (15.1)
16 (26.2)
0.109
Postoperative hemorrhage, (%)
11 (8.2)
7 (9.6)
4 (6.5)
0.524
Iatrogenic pneumonia, (%)
24 (17.9)
10 (13.7)
14 (23.0)
0.164
Other (miscellaneous)d, (%)
8 (6)
4 (5.5)
4 (6.6)
0.537
aAbdominal closure refers to the delayed primary fascial closure, partial fascial closure, skin grafting, or skin-only suturing. bThe survivals until abdominal closure. cThe survivals until hospital discharge. dOther complications included catheter-associated infection, deep venous thrombosis, and pulmonary embolism.
