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Gastroenterology Research and Practice
Volume 2014, Article ID 392562, 7 pages
http://dx.doi.org/10.1155/2014/392562
Research Article

Common Bile Duct Dilatations in Asymptomatic Neonates: Incidence and Prognosis

1Department of Pediatrics, Chi Mei Medical Center, Liouying, No. 201 Taikang, Taikang Village, Liouying District, Tainan City 736, Taiwan
2Department of Pediatrics, Mackay Memorial Hospital, No. 690 Section 2, Guangfu Road, East District, Hsinchu City 30071, Taiwan
3Department of Pediatrics, Taipei Medical University, No. 250 Wu-Hsing Street, Taipei City 100, Taiwan
4Department of Pediatrics, Mackay Memorial Hospital, No. 92 Section 2, Zhongshan North Road, Taipei City 10449, Taiwan

Received 15 October 2013; Revised 10 February 2014; Accepted 10 February 2014; Published 19 March 2014

Academic Editor: Gianfranco D. Alpini

Copyright © 2014 Shun-Feng Lin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. This retrospective study reviewed 213 asymptomatic neonates with common bile duct (CBD) dilatations diagnosed via ultrasound to evaluate their incidence and outcomes. Materials and Methods. From August 2001 to July 2010, 18,230 abdominal ultrasound scans were performed as newborn screening. There were 213 (1.17%) cases of CBD dilatation. Dilatation of neonatal CBD was defined when its diameter was ≥2 mm. The neonates’ birth history, CBD size, and follow-up results were analyzed. Results. In the 213 infants, four cystic dilatations (1.88%, 4/213) that were eventually diagnosed as choledochal cysts (CC). Among 209 neonates with fusiform dilatations (size 2.0–6.7 mm), 77 had ultrasound follow-up and 87% of them resolved spontaneously which were diagnosed as transient CBD dilatation (TCBDD). Eighty percent of TCBDDs resolved within 6 months. Patients with initial CBD size ≥3 mm had significantly lower resolution rate and neonates whose mothers are older than 35 years took longer time to resolve. Conclusion. The incidence of CBD dilatation in asymptomatic neonates was 1.17%. Eighty percent of TCBDDs resolved within 6 months. Regular ultrasound follow-up every 6 months may be appropriate for asymptomatic neonates with fusiform CBD dilatations to ensure resolution or progression.