Difference in Early Activation of NF-κB and MCP-1 in Acinar-Cell-Rich versus Fibrotic Human Pancreas Exposed to Surgical Trauma and Hypoxia
Figure 1
NF-κB activation in acinar-cell-rich pancreas. Immediately after sampling, parallel portions of each tissue specimen were immersed in saline and kept at room temperature for 15 minutes (a), 2.5 hours (b), 4 hours (c), or 6 hours (d), after which they were fixed and processed for immunohistochemical analysis. The slides were counterstained with hematoxylin. Slight staining of acinar cell nuclei can be seen at 15 minutes (a) and significant amplification is observed at 2.5 hours (b). Almost every acinar cell nucleus is stained at 4 hours (c) and activation decreases at 6 hours (d).
